The game ultimately came down to the 2 ISO possessions George had on Russell.
This is a tough spot for Luke to be in. Russell may have taken up the challenge to get a chance to improve his defense, who, isn't only seen as soft defensively among Laker fans, but in the entire league. Paul George saw that help defense wasn't coming, smelled blood, and went in for the kill twice, on back-to-back possessions. In retrospect, it was the wrong strategy decision by Luke.
But long term, this is a tough spot for Luke to be in. The only way to get Russell to to take it upon himself to improve his perimeter defense is to give him the opportunity to prove himself in clutch situations. If Phil Jackson was coaching and D'Angelo was calling for that 1on1 matchup, Phil would have given it to him. Popovich and Pat Riley wouldn't have.
The results of the game were actually encouraging. The Lakers had superior talent and should have won. The plan is working. What's concerning is how disheartened everyone on the team looked after the loss, like they just lost Game 5 of a playoff series.
We are 4 games in the season. It was a tough loss, so what. Get a nice dinner, get some rest, and get at it again tomorrow.