As far as the PC version is concerned, you don't have to sell your organs to get an ultra gaming computer.
With a Radeon HD7970 (3GB VRAM) you can run the game with maxed settings at 1920x1080. I got everything "Very High", FXAA on, MSAA x8. Anisotropic Filtering doesn't have a big impact. The only things I have deactivated are the "Advanced Settings" like "HR Shadows" and "HD Streaming When Flying". I tried to set them on and the FPS dropped but they don't change the quality that much. Maybe on a 4K screen they would, though.
I read on the Net that some wackos tried it out on a triple 4K and it sucked up 14GB VRAM!
Anyway, it's a really well-optimized game for PC.