It depends on how they do Thanos in the next movie.
Spiderman's and Batman's enemies won't reach the level of power of Loki (or even Hulk). Again, this goes back to the very nature of the original writing because Marvel has god-like heroes and villians which makes it more of a challenge to construct a movie in which they are in any danger. However, that will all change with Thanos. I mean, we're talking about a guy that can rape Silver Surfer, beat Hulk, beat Thor, possibly go toe-to-toe with Galactus, probably take out Superman, remember Gladiator? Thanos would pwn him.
I don't see the comparison with The Matrix at all.
Edited by Windu, September 07, 2012 - 02:14 PM.